i was just surfing through some recent science and innovation updates and i found one of the most research project which is being given emphasis in many labs across world that is " Stretching of DNA". i am not a biology person so couldn't understand it much but would like to.
According to recent results
Researchers in Europe have literally unravelled a mystery that has been puzzling scientists for years: what happens to a molecule of DNA when it is stretched to its breaking point. The question is important because DNA is subjected to a range of mechanical manipulations within the cell: it can be folded, unfolded, coiled and uncoiled, unzipped and zipped up again. A detailed understanding of the elastic properties of DNA can give scientists key insights into interactions of DNA and the proteins that carry out these manipulations.
Almost two decades ago it was shown that when a molecule of double-stranded DNA is pulled from either end, it undergoes a peculiar transition. Initially the molecule resists stretching. Then, at a force of 65 piconewtons, the polymer suddenly surrenders and stretches to 1.7 times its original length with little additional force. It then becomes resistant to stretching once more.
research on strethcing of DNA from my point of view is imp may be for the study of enzymes interacting with Dna or to obtain some kind of genetic information..from 1997 research is going on this project and still scientist are working on.
here are some links for more information
http://www.rsc.org/chemistryworld/News/2009/October/19100902.asp
http://www.sciencedaily.com/releases/2006/12/061206091654.htm#
http://www.lbl.gov/Science-Articles/Archive/PBD-stretched-DNA.html
if anyone of you could understand this aspect mcuh better pls feel free to comment.
With love & peace
Abhinav
Setting the metallic hydrogen record straight
9 years ago
